Functional Imaging by Controlled Nonlinear Optical Phenomena

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Functional Imaging by Controlled Nonlinear Optical Phenomena

Wataru Watanabe,Kazuyoshi Itoh,Keisuke Isobe

O-Book

978-1-118-75187-9

September 2013

Available on Wiley Online Library

Description

Ultrafast lasers allow high-precision imaging and manipulation for biological and medical applications. Nonlinear optical microscopy has provided researchers with unique possibilities of three-dimensional imaging of biological cells and tissues. Nonlinear optical imaging technique is a rapidly emerging research area with widespread fundamental research and clinical applications. Nonlinear optical imaging allows both structural and functional imaging with cellular level resolution imaging in biological systems. The introduction of endogenous or exogenous probes can selectively enhance contrast for molecular targets in a living cell as well as supply functional information on processes. With the aim to control nonlinear optical processes and to obtain functional images, nonlinear optical processes can be controlled by photo-controlled probes and/or parameters of ultrafast laser pulses, such as time, space, polarization, and phase.

This book gives an overview of the nonlinear optical process by ultrafast laser pulses and explains how the basics of nonlinear optical microscopy led to the most advanced techniques of photo-controlled nonlinear optical microscopy.

About the Author

KEISUKE ISOBE, DEng, is a Research Scientist at the RIKEN Center for Advanced Photonics.

WATARU WATANABE, DEng, is a Professor in the Department of Electrical & Electronic Engineering, College of Science and Engineering, at Ritsumeikan University.

KAZUYOSHI ITOH, DEng, is a Professor Emeritus and Research Professor at the Science Technology Entrepreneurship Laboratory (E-Square), Osaka University.

Series

Wiley Series in Biomedical Engineering and Multi-Disciplinary Integrated Systems

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