The study of nonlinearities in physiology has been hindered by the lack of effective ways to obtain nonlinear dynamic models from stimulus-response data in a practical context. A considerable body of knowledge has accumulated over the last thirty years in this area of research. This book summarizes that progress, and details the most recent methodologies that offer practical solutions to this daunting problem. Implementation and application are discussed, and examples are provided using both synthetic and actual experimental data. This essential study of nonlinearities in physiology apprises researchers and students of the latest findings and techniques in the field.
About the Author
Vasilis Z. Marmarelis, PhD, received his diploma in electrical and mechanical engineering from the National Technical University of Athens and his MS in information science and PhD in engineering science (bio-information systems) from the California Institute of Technology. He is currently a professor in the faculty of the Biomedical and Electrical Engineering Departments at USC, where he served as chairman of Biomedical Engineering from 1990 to 1996. He is also Codirector of the Biomedical Simulations Resource (BMSR), a research center dedicated to modeling and simulation of physiological systems and funded by the National Institutes of Health through multimillion-dollar grants since 1985.
