A one-stop resource for researchers, developers, and post graduate students in pharmaceutical science. This handbook and ready reference provides detailed, but not overloaded information -- presenting the topic without unnecessarily complex formalism. As such, it gives a systematic and coherent overview of disordered materials for pharmaceutical applications, covering fundamental aspects, as well as preparation and characterization techniques for the target-oriented development of drug delivery systems based on disordered crystals and amorphous solids. Special attention is paid to examine the different facets and levels of disorder in their structural and dynamic aspects as well as the effect of disorder on dissolution and stability. Chapters on processing induced disorder and on patenting issues round off the book. As a result the book helps overcoming the challenges of using these materials in the pharmaceutical industry. For pharmaceutical and medicinal chemists, materials scientists, clinical physicists, and pharmaceutical laboratories looking to make better and more potent pharmaceuticals.
About the Author
Marc Descamps is Professor for solid state physics and Head of the Technological Research Group "Therapeutic Materials" at the University of Lille, France. He is the author of more than 160 publications in international journals and he has collaborated with several large pharmaceutical companies. His research interests include: phase transitions in molecular materials, disordered crystals, molecular glasses and studies of the structural and dynamic properties of pharmaceutical solids by a variety of physicochemical techniques.
