In this epic work Charles Pasternak traces life on earth from the most primitive cells, through ancient civilizations and the great artists, scientists, writers and explorers of the past, to the genetic engineers of today. In a thought-provoking view of the history of mankind he argues that it is not any single genetic difference, but a combination of very subtle changes that has enabled man to exercise a greater propensity for quest. It is this that has led to our domination over other species.

Conversely, he argues that a weakening in the exercise of this basic instinct among the western nations will lead to a decline in their influence, relative to that of eastern populations such as those of China and India, south east Asia and Japan.