DNA-based nanotechnology has advanced tremendously in the past 30 years to become a key player in many different fields of science and research. Nucleotides, no longer merely building blocks of life, can be used like Lego bricks to create new functional entities. These DNA nanostructures play a major role in soft materials, electronics, diagnostics and medicinal chemistry.

This book presents a unique collection of accounts of the current research and technology on modified nucleotides and functional DNA systems derived thereof, with contributions from the world’s leading experts. Each article describes the basic research, as well as outlining novel applications and future directions of the field. The contents include:

• (Non-)covalently modified DNA with novel functions

• DNA wires and electron transport through DNA

• Oligonucleotides in sensing and diagnostic applications

• Conjugation of DNA with biomolecules and nanoparticles

• Alternative DNA structures, switches and nanomachines

With new results being published on a daily basis, DNA nanotechnology continues to influence materials, medicinal and biological sciences, driven by demands for applications. Intended for both newcomers and experienced researchers in DNA nanotechnology, this book is an indispensable resource in the lab as well as in the teaching class.