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Cancer Vaccines and Tumor Immunity

ISBN: 978-0-470-07474-9

January 2008

352 pages

Description

A team of expert contributors takes a focused look at the emerging area of cancer vaccines and tumor immunity

Cancer vaccine development is one of the latest therapeutic tools being used in our fight against cancer. Cancer vaccine research has progressed from a small-scale academic enterprise to an applied science requiring a large clinical research infrastructure. Although cancer vaccines remain a work in progress, intriguing clinical results have been noted and new ideas continue to hold great promise for the field.

Cancer Vaccines and Tumor Immunity offers a review of the basic scientificdiscoveries that have moved forward into clinical trials. Presented in the context of real-world human research and experimentation, these major scientific advances demonstrate how our understanding of immune activation,T-regulatory cells, and autoimmunity will impact cancer vaccine design. The authors also explain how vaccination in the context of bone marrow transplantation will open new avenues for clinical study in the future.

Cancer Vaccines and Tumor Immunity is a one-stop resource for professionals and trainees in both academic and commercial institutions who are looking for a concise overview of the history of the field, current research, and likely advances that will shape the future of cancer vaccines. It also serves as a valuable supplementary text for graduate students studying in related fields.

About the Author
Rimas J. Orentas, PhD, is Associate Professor in the Department of Pediatrics, Section of Hematology-Oncology, and holds joint appointments in the Departments of Medicine and Microbiology and Molecular Genetics at the Medical College of Wisconsin in Milwaukee, Wisconsin.

James W. Hodge, PhD, is a Senior Scientist in the Laboratory of Tumor Immunology and Biology at the National Cancer Institute in Bethesda, Maryland.

Bryon D. Johnson, PhD, is Associate Professor in the Department ofPediatrics, Section of Hematology-Oncology at the Medical College of Wisconsin in Milwaukee, Wisconsin.