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Cancer Diagnostics with DNA Microarrays
ISBN: 978-0-471-78407-4
August 2006
203 pages
This text provides a first-time comprehensive review and analysis of the state of the art in clinical applications of DNA microarray data in cancer diagnostics. The acclaimed author, an international authority in the field, reviews published clinical trials for ten common cancer types. Moreover, the text provides a meta-analysis of these trials to highlight where the results concur.
The author begins with a discussion of the state of DNA microarray technology, emphasizing important aspects of data analysis. Emerging technologies within the field of DNA microarrays are presented. Next, readers learn the statistical analysis techniques needed to interpret the data. Finally, the author examines some major human cancer types where microarrays have been applied with success. The author concludes, based on the evidence and his own studies in the field, that the results are so convincing for several cancer types that DNA microarrays are ready to be deployed in clinical practice.
The text provides many features for researchers and clinicians who want to use microarrays as a hands-on diagnostic tool, including:
With the promise of DNA microarrays leading to more accurate cancer diagnoses, this text is an invaluable guide that opens the door to better care for cancer patients.