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Biomarker Validation: Technological, Clinical and Commercial Aspects

ISBN: 978-3-527-68067-2

February 2015

264 pages

Description

From the Contents:

• Biomarkers – Past and Future

• Quantitative Proteomics Techniques in Biomarker Discovery

• Biomarker Qualification: A Company Point of View

• Biomarker Discovery and Medical Diagnostic Imaging

• Breath: An Often Overlooked Medium in Biomarker Discovery

• HTA in Personalized Medicine Technologies

• Bone Remodeling Biomarkers: New Actors on the Old Cardiovascular Stage

• Identification and Validation of Breast Cancer Biomarkers

• Evaluation of Proteomic Data: From Profiling to Network Analysis by Way of Biomarker Discovery

• Biomarkers: From Discovery to Commercialization

• Clinical Validation

• Genomics and Proteomics for Biomarker Validation

For Biochemists, Clinical Chemists, Oncologists, Laboratory Medics, and Analytical Research Institutes.

About the Author
Harald Seitz studied Biochemistry at the Free University of Berlin, accomplished his PhD working at the MPI for Molecular Genetics in 2000 and finished his habilitation at the University of Kassel in 2012. After working for nearly 10 years at the MPI for Molecular Genetics he moved to the Fraunhofer Institute for Biomedical Engineering in 2011. The focus of his work is on high throughput techniques especially all kinds of protein and peptide microarrays and in vitro diagnostics.

Sarah Schumacher studied Biology at the Free University of Berlin and completed her M.Sc. at the Humboldt University of Berlin. Before she started her PhD in 2013, she worked at the MPI for Molecular Genetics in Berlin and moved to the Fraunhofer IBMT in Potsdam-Golm in 2011. Her research interest is on biomarker and antibody validation.