Medicinal Inorganic Chemistry represents a key area that comprises medical and biological inorganic chemistry. It is also currently an area of great excitement and achievements, where new approaches and ideas are thriving. The fi eld of metals in medicine represents approximately a $3 billion/year industry. Pt-based cancer therapeutics are the major contributors to this bottom line, but relevant clinical success has been achieved also in the area of Tc- and Gd-based imaging agents. It has become increasingly apparent, however, that metal-based pharmaceuticals can play a prominent role in areas outside of imaging and oncology, including those associated with the diagnosis and treatment of metabolic and genetic disorders, cardiovascular diseases, gene therapy, infl ammation, riperfusion injury, stroke, diabetes, ALS, malaria, and neurological diseases, to name but a few. This book is written by an international panel of experts in the fi eld and provides the reader with a ready reference to state-of-the-art Medicinal Inorganic Chemistry.
It is a must-have for Inorganic, Medicinal, and Bioinorganic Chemists, as well as Chemists working with Organometallics and in Industry.
About the Author
Enzo Alessio was born in 1958, studied chemistry at the University of Trieste (Italy) and received his PhD from the University of Ferrara (Italy) in 1989. After a NATO-CNR postdoctoral fellowship with Luigi G. Marzilli at Emory University (Atlanta), he became fi rst Research Associate and then Associate Professor of Inorganic Chemistry at the University of Trieste, where he is now director of the PhD School in Chemistry. He is co-author of more than 150 publications and 10 patents in the fi elds of coordination chemistry, metal-based anticancer drugs, and metal-driven construction of supramolecular architectures, in particular multi-chromophore assemblies for photophysical applications.
