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Active Pharmaceutical Ingredients in Synthesis: Catalytic Processes in Research and Development
ISBN: 978-3-527-80726-0
October 2018
456 pages
Presents the most effective catalytic reactions in use today, with a special focus on process intensification, sustainability, waste reduction, and innovative methods
This book demonstrates the importance of efficient catalytic transformations for producing pharmaceutically active molecules. It presents the key catalytic reactions and the most efficient catalytic processes, including their significant advantages over comparable previous methods. It also places a strong emphasis on asymmetric catalytic reactions, process intensification (PI), sustainability and waste mitigation, continuous manufacturing processes as enshrined by continuous flow catalysis, and supported catalysis.
Active Pharmaceutical Ingredients in Synthesis: Catalytic Processes in Research and Development offers chapters covering: Catalysis and Prerequisites for the Modern Pharmaceutical Industry Landscape; Catalytic Process Design: The Industrial Perspective; Hydrogenation, Hydroformylation, and Other Reductions; Oxidation; Catalytic Addition Reactions; Catalytic Cross-Coupling Reactions; Catalytic Metathesis Reactions; Catalytic Cycloaddition Reactions: Coming Full Circle; Catalytic Cyclopropanation Reactions; Catalytic C–H insertion Reactions; Phase Transfer Catalysis; and Biocatalysis.
Covering a topic of great interest for synthetic chemists and R&D researchers in the pharmaceutical industry, Active Pharmaceutical Ingredients in Synthesis: Catalytic Processes in Research and Development is a must-read for every synthetic chemist working with APIs.