This book covers the fundamentals, experimental procedures, and applications of dried blood spot (DBS) sampling in combination with various qualitative and quantitative analytical techniques. This includes sample collection, storage, transportation, and sample preparation for various analysis. Experimental examples in newborn screening, toxicokinetics and pharmacokinetics, and forensics are also given. Finally, the book provides an overview of trends in quantitative and qualitative analysis of DBS samples as well as future perspectives. This provides a valuable working guide to researchers, professionals, and students in healthcare, medical science, diagnosis, chemistry, and pharmaceuticals.
About the Author
WENKUI LI currently serves as Senior Fellow in the Department of Drug Metabolism & Pharmacokinetics at Novartis Institutes for BioMedical Research, where he focuses on regulated LC-MS/MS bioanalysis for the toxicokinetic and pharmacokinetic assessment of drug candidates. Dr. Li is a member of the editorial board of Biomedical Chromatography.
MIKE S. LEE currently serves as a provider of consulting services specializing in pharmaceutical analysis, accelerated drug discovery and development strategies, and analytical technologies. He has delivered many presentations as invited speaker, plenary speaker, and workshops instructor in the areas of drug discovery and development at universities, conferences, and industrial technical centers. He has published numerous papers and books and obtained two U.S. patents.
