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Assay Development: Fundamentals and Practices

ISBN: 978-0-470-58312-8

June 2010

448 pages

Description
The first comprehensive, integrated treatment of the subject, Assay Development: Fundamentals and Practices covers the essentials and techniques involved in carrying out an assay project in either a biotechnology/drug discovery setting or a platform setting. After discussing the basics, it explains the treatment of assays for purified protein, cell-based assays, and high-throughput screening. It includes good practices and case studies. This is a premier resource for biotechnologists, analytical chemists, biochemists, medicinal chemists, toxicologists, and others, and an excellent text for professors preparing students to enter the biotechnology and pharmaceutical industries.
About the Author

Ge Wu, PhD, is Director of Assay Development at Iris International. He obtained his doctorate in biochemistry from UCLA, performed postdoctoral work at Harvard Medical School, and was a member of the faculty at Cornell University Medical College. Prior to joining Iris International, he worked at Merck & Co., Caliper Technologies, Amphora Discovery, and FivePrime Therapeutics. He is the founding Director of Assay Development and Screening at FivePrime Therapeutics. Dr. Wu is a leading figure in assay development and screening in biopharmaceutical discovery using primary cell assay and the author of an acclaimed review in this subject.