Molecules and Medicine provides, for the first time ever, a completely integrated look at chemistry, biology, drug discovery, and medicine. It delves into the discovery, application, and mode of action of more than one hundred of the most significant molecules in use in modern medicine. Opening sections of the book provide a unique, clear, and concise introduction, which enables readers to understand chemical formulas.
About the Author
E. J. Corey has been a Professor at Harvard University since 1959. He was educated at The Massachusetts Institute of Technology (1945-1950) and served as a faculty member at the University of Illinois from1951 to 1959. He is the 1990 Nobel Laureate in Chemistry, and the recipient of over seventy international awards and honorary degrees, including the U.S. National Medal of Science, the Japan Prize in Science, and the Priestley Medal of the American Chemical Society. He is amember of the U.S. National Academy of Sciences and the U.S. National Institute of Medicine. Professor Corey is the author of more than 1,000 publications and is one of the most cited authors in science.
Barbara Czakó completed undergraduate studies at the University of Debrecen, Hungary, where she worked with Dr. Sándor Berényi. She obtained a Master of Science degree at the University of Missouri-Columbia with Professor Shon R. Pulley. Dr. Czakó received her Ph.D. degree (2006) in synthetic organic chemistry under the guidance of Professor Gary A. Molander at the University of Pennsylvania. Currently she is a postdoctoral fellow with Professor E.J. Corey at Harvard University. In 2005 she published with László Kürti the textbook Strategic Applications of Named Reactions in Organic Synthesis.
László Kürti was born and raised in Hungary. He received his diploma from the University of Debrecen, Hungary, where he conducted research in the laboratory of Professor Sándor Antus. Subsequently he received his Master of Science degree at the University of Missouri-Columbia working with Professor Michael Harmata, and his Ph.D. degree (2006) in synthetic organic chemistry under the supervision of Professor Amos B. Smith III (the University of Pennsylvania). Currently he is a Damon Runyon Cancer Fellow in the group of Professor E.J. Corey at Harvard University. In 2005 he published with Barbara Czakó the textbook Strategic Applications of Named Reactions in Organic Synthesis.
Features
Authoritatively co-written by a Nobel Laureate, this book offers a wide range of readers an understanding of medicinal agents and human illness at the molecular level.\
Organized by disease category for easy use as a reference or teaching text, coverage includes inflammatory, cardiovascular, and metabolic diseases, reproductive diseases, osteoporosis, glaucoma, ulcer, auto-immune and oxygen transport diseases, malignant diseases, and diseases of the central nervous system
Focuses on more than 120 of the most important and commonly used drugs such as cholesterol lowering medicines, anti-clotting agents, oxytocins, Viagra, antibiotics, antimalarial, cancer drugs, and pain medicines (Aleve, analgesics, migraine medications), insomnia medications, anti-obesity medications, anti-smoking medications, anti-epileptic medications, and anti-depressants
Provides a brief step-by-step how-to on reading and understanding chemical structures of molecules, followed by a complementary introduction to protein structures
Supplementary focus sections provide a biomedical background to aid in understanding, with coverage including inflammation, metabolic syndrome, immunology, drug resistance, cancer and neurotransmission
Full and thoroughly referenced to the primary literature, all protein structures are also linked to the publicly available online protein database
