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Glycobiology of the Immune Response, Volume 1253

ISBN: 978-1-573-31839-6

May 2012

Wiley-Blackwell

252 pages

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Description

Carbohydrates are ubiquitous, essential molecules, as important as nucleic acids and proteins yet less well understood.  Mounting data demonstrate that microbial and mammalian glycans and their protein-binding partners (lectins) play central roles in all innate and adaptive immune responses.  Indeed, programmed remodeling of host glycans can modulate infection, autoimmunity, and cancer, while microbial glycoconjugates can serve as canonical innate receptor agonists that induce B cell and T cell activation.  Glycobiology of the Immune Response explores the integration of state-of-the-art glycobiology and immunology to raise awareness of the multifaceted roles of glycans and lectins in the immune system

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About the Author

Gabriel Rabinovich and Brian Cobb are the authors of Glycobiology of the Immune Response, Volume 1253, published by Wiley.