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Asymmetric Hydrogenation and Transfer Hydrogenation

ISBN: 978-3-527-82230-0

April 2021

400 pages

Description
Asymmetric Hydrogenation and Transfer Hydrogenation

Discover the latest developments in homogeneous asymmetric (transfer) hydrogenation with this up-to-date resource

Asymmetric Hydrogenation and Transfer Hydrogenation delivers a current and cutting-edge investigation of homogenous asymmetric hydrogenation and transfer hydrogenation reactions of prochiral substrates by using organometallic catalysts (like ruthenium, rhodium, iridium, iron, and copper) and organic catalysts.

Distinguished researchers and editors Virginie Ratovelomanana-Vidal and Phannarath Phansavath also offer readers a comprehensive walkthrough of substituted ketones through dynamic kinetic resolution, as well a presentation of the mechanisms and application of asymmetric hydrogenation reactions to the synthesis of biologically relevant compounds.

The book comprehensively details its complex subject matter clearly and plainly and covers everything from catalyst development and reactions to mechanisms and applications in academia and industry. The papers included within come from many of the leading voices in their respective fields and represent the newest and best research available today.

Compiled for researchers and private-industry chemists alike, Asymmetric Hydrogenation and Transfer Hydrogenation also discusses a wide variety of other topics like:

  • A discussion of the development of chiral metal catalysts for asymmetric transfer hydrogenation
  • Several examinations of asymmetric transfer hydrogenation of a variety of chemical groups, including ketones, aryl and heteroaryl ketones, substituted ketones, and heteroaromatic compounds, alkenes, and imines
  • An exploration of the mechanism of asymmetric hydrogenation and continuous flow asymmetric hydrogenation
  • A full and thorough treatment of the industrial applications of asymmetric hydrogenation

Perfect for catalytic chemists, chemists working on or with organometallics, organic chemists, natural product chemists, pharmaceutical chemists, medicinal chemists, and industrial chemists, Asymmetric Hydrogenation and Transfer Hydrogenation also belongs on the bookshelves of research and university institutes and libraries who wish to expand their selection on a topic fundamental to organic synthesis.

About the Author

Virginie Ratovelomanana-Vidal is CNRS Research Director at Chimie ParisTech in France. Her research interests focus on transition-metal catalysis for atom- and step-economical reactions and the design of atropisomeric ligands (Synphos and Difluorphos) for asymmetric catalysis. The synthesis of biorelevant targets is also a focus in her group. She was Chair of the Division of Organic Chemistry of the French Chemical Society (2009–2012).

Phannarath Phansavath is Associate Professor at Chimie ParisTech in France. Her research interests include total synthesis of biologically relevant natural products and transition metal-catalyzed asymmetric reactions.