* presents state-of-the-art interventions for human immunologic disease with a focus on therapies rather than pathophysiology.

* total revision including 14 new chapters and 36 new contributors.

* organized by three classes of therapy: Drugs (e.g. corticosteroids), Biologic Agents (e.g. cytokines), and Maneuvers (e.g. transplantation).

* covers the full spectrum of therapeutic interventions.

* incorporates coverage of scientific research with the discussion of clinical application.

* edited by experts from four Harvard hospitals.