Now in a revised edition, Comparative Pharmacokinetics: Principles, Techniques, and Applications presents the principles and techniques of comparative and veterinary pharmacokinetics in a detailed yet practical manner. Developed as a tool for ensuring that pharmacokinetics studies are properly designed and correctly interpreted, the book provides complete coverage of the conceptual basis of pharmacokinetics as used for quantifying biological processes from the perspectives of physiology and medicine. New chapters have been added on quantitative structure permeability relationships and bioequivalence, and a number of existing chapters have been significantly revised and expanded to provide a current resource for veterinary and comparative pharmacokinetics.
About the Author
Jim Riviere, DVM, PhD, DSc (hon), ATS, is the Burroughs Wellcome Fund Distinguished Professor of Pharmacology, Alumni Distinguished Graduate Professor, and Director of the Center for Chemical Toxicology Research and Pharmacokinetics at North Carolina State University, and Editor of the Journal of Veterinary Pharmacology and Therapeutics.
Features
Provides a detailed but understandable reference on the conceptual basis of veterinary and comparative pharmacokinetics
Covers practical applications to both animal and human medicine
Offers essential information for ensuring that pharmacokinetics studies are correctly designed and interpreted
Includes new chapters on quantitative structure permeability relationships and bioequivalence, as well as fully revised and expanded chapters throughout
Presents a fully rewritten chapter on simultaneous pharmacokinetic-pharmacodynamic modeling to reflect its newly widespread role in comparative medicine
Facilitates the reader in making conceptual linkages between theory and applications with expanded cross-referencing between topics