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Nuclear Receptors as Drug Targets

Raimund Mannhold (Series Editor), Hugo Kubinyi (Series Editor), Eckhard Ottow (Editor), Gerd Folkers (Series Editor), Hilmar Weinmann (Editor) 

ISBN: 978-3-527-62330-3

September 2008

522 pages

To Purchase this product, please visit
https://dev.store.wiley.com/en-ca/Nuclear+Receptors+as+Drug+Targets-p-9783527623303

Nuclear Receptors as Drug Targets

Raimund Mannhold,Hugo Kubinyi,Eckhard Ottow,Gerd Folkers,Hilmar Weinmann

E-Book
978-3-527-62330-3
September 2008
CAD $300.99
Hardcover
978-3-527-31872-8
October 2008
CAD $375.95
Description
Nuclear receptors are the site of action for some of the most widely used medications, namely oral contraceptives and related drugs derived from steroid hormones. Recent research has uncovered their pivotal role in a range of human diseases, including diabetes and metabolic syndrome, triggering a new wave of drug discovery efforts focused on this class of molecular targets.
Edited by two experts working at the pioneering pharmaceutical company and major global player in hormone-derived drugs, this handbook systematically treats the drug development aspects of all human nuclear receptors, including such recently characterized receptors as PPAR, FXR and LXR, and modern tools for nuclear receptor research.
With its contributions from authors working at leading pharmaceutical companies around the world providing examples and real-life data from their own experience, this is an invaluable reference for medicinal chemists, biochemists, molecular biologists, pharmacologists and those working in the pharmaceutical industry.
About the Author
Eckard Ottow is the head of medicinal chemistry at Schering AG in Berlin (Germany). He studied Chemistry at the University of Hannover (Germany) and received his PhD degree in 1982. He joined Schering AG in 1983, first in the field of endocrinology and later in oncology and CNS. In 2002, he was appointed to his present position as head of medicinal chemistry. He is also a honorary professor at the Technical University of Berlin.

Hilmar Weinmann studied Chemistry at the universities of Tubingen and Hannover (Germany). He joined Schering in 1995, where he is currently a department head of Medicinal Chemistry. His main fields of expertise are in oncology, dermatology and gender healthcare.
Series
Methods & Principles in Medicinal Chemistry
To Purchase this product, please visit
https://dev.store.wiley.com/en-ca/Nuclear+Receptors+as+Drug+Targets-p-9783527623303