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Natural Lactones and Lactams: Synthesis, Occurrence and Biological Activity

ISBN: 978-3-527-66693-5

September 2013

392 pages

Description
Lactones and lactams, cyclic molecules found in nature, yet so versatile that they can be reused in both the pharmaceutical industry and as chiral building blocks in organic synthesis, are the focus of this book.
Although there a numerous tomes on heterocyclic compounds and natural products, this text fills the gap for an up-to-date summary of recently developed and improved synthetic methods for the preparation of the most important classes of lactones and lactams.
Each chapter deals with the general and most recent synthetic methods leading to a specific class of lactone or lactam to enable quick accessto the procedure you desire. With brief descriptions of the occurrence and biological or pharmaceutical activity of each compound class, the authors have ensured that this book is comprehensive in its coverage.
A valuable resource for organic, bio-, and medicinal chemists in academia and industry wanting to learn about successful synthetic routes to important natural products and use this as inspiration for their own work in the lab.
About the Author
Tomasz Janecki was born in Lodz (Poland) and studied chemistry at the Lodz University of Technology. He obtained his doctorate in 1981 under the guidance of Ryszard Bodalski. After postdoctoral appointments at Strathclyde University (Peter Pauson) and the University of Texas at Austin (Josef Michl and Karl Folkers), he began an independent research career and completed his "Habilitation" at the Lodz University of Technology in 1996. Currently, he is a Full Professor of Organic Chemistry at the same university. His main research interest is the application of organophosphorus reagents in stereoselective synthesis of biologically important classes of organic compounds.