This comprehensive handbook highlights the triumph and developments of MALDI-TOF mass spectrometry in diagnostic approaches to clinical microbiology over the past decade, and provides insight into new technologies including tandem MS/MS. Presenting the reader with detailed coverage of current research and future opportunities, this volume, divided into two parts, with 21 chapters, includes such topics as:

• Applications of MALDI-TOF Mass Spectrometry in Clinical Diagnostic Microbiology
• The Potential of MALDI-TOF MS to Distinguish between Taxonomically Similar Species that Manifest Different Infections
• Microbial DNA Analysis by MALDI-TOF Mass Spectrometry
• Development and Application of MALDI-TOF MS for Detection of Resistance Mechanisms
• Determination of Antimicrobial Resistance using Tandem Mass Spectrometry
• Top-Down Proteomics in the Study of Microbial Pathogenicity
• Proteogenomics of Non-Model Microorganisms

Primarily aimed at clinical microbiologists, diagnostic technologists, biomedical scientists, researchers, clinicians, academics and scientists in bio-resource centres, this book is also relevant to researchers, post-graduate scientists, technologists in the food industry, pharmaceuticals and agriculture.