Carbohydrates are important storage molecules, constituents of nucleic acids and biological recognition markers. Synthetic carbohydrates are important food additives, building blocks for polymers and have also been used as drugs. Concise yet complete, this is a succinct introduction to the topic, covering both basic chemistry as well as such advanced topics as high-throughput analytics and glycomics -- in one handy volume. This improved and expanded 3rd edition features all-new material on combinatorial synthesis of carbohydrates and carbohydrate biodiversity, and each chapter now contains study questions for self-learning and classroom teaching. From the contents: * Introduction to Carbohydrates * Structure of Saccharides * Protecting Groups for Carbohydrates * O-Glycoside Synthesis * Modifications and Functionalizations of the Sugar Ring * Glycoconjugates - Structure and Biosynthesis * Combinatorial Synthesis of Carbohydrates * Glycobiology and Glycomics * Purification and Analysis of Carbohydrates * The Literature of Carbohydrate Chemistry Didactically written by an experienced lecturer and graduate student advisor, the text is backed by practical examples and many study questions tailored to students' needs.
About the Author
Thisbe Lindhorst holds the Chair of Organic Chemistry at the University of Kiel (Germany). She graduated from Münster University in 1988, completing her Ph.D. in Organic Chemistry at the University of Hamburg in 1991. She then spent a postdoctoral period with S. G. Withers at the University of British Columbia in Vancouver (Canada) before returning to Hamburg. In 2000 she was appointed full professor at the University of Kiel. Her research interests focus on natural product synthesis, carbohydrate and dendrimer chemistry.
New to Edition
The third edition has seen a major revision of both contents and layout, bringing the book up to current international textbook standards. The most important novelty is the inclusion of more than 150 problems and questions (20 to 30 for each chapter). Layout and graphics have been completely redone, with visual aids to guide the students through the text and emphasize important concepts and learning goals.
The contents have been updated to include recent developments such as solid phase oligosaccharide synthesis, novel protecting groups and glycoconjugates. To capture the recent trend to a systems level description of carbohydrate biology, there are two new sub-chapters, one on the structural diversity of carbohydrates, and another one on the simultaneous detection of multiple carbohydrate species by microarrays, also known as the "glycomics" approach.
