Basic Biostatistics for Geneticists and Epidemiologists: A Practical Approach

Robert C. Elston, Department of Epidemiology and Biostatistics,Case Western Reserve University, USA

William D. Johnson, Pennington Biomedical Research Center,Louisiana State University, USA

Anyone who attempts to read genetics or epidemiology research literature needs to understand the essentials of biostatistics. This book, a revised new edition of the successful Essentials of Biostatistics has been written to provide such an understanding to those who have little or no statistical background and who need to keep abreast of new findings in this fast moving field. Unlike many other elementary books on biostatistics, the main focus of this book is to explain basic concepts needed to understand statistical procedures.

This Book:

• Surveys basic statistical methods used in the genetics and epidemiology literature, including maximum likelihood and least squares.
• Introduces methods, such as permutation testing and bootstrapping, that are becoming more widely used in both genetic and epidemiological research.
• Is illustrated throughout with simple examples to clarify the statistical methodology.
• Explains Bayes' theorem pictorially.
• Features exercises, with answers to alternate questions, enabling use as a course text.

Written at an elementary mathematical level so that readers with high school mathematics will find the content accessible. Graduate students studying genetic epidemiology, researchers and practitioners from genetics, epidemiology, biology, medical research and statistics will find this an invaluable introduction to statistics.