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Bacterial Virulence: Basic Principles, Models and Global Approaches

ISBN: 978-3-527-32326-5

March 2010

Wiley-Blackwell

340 pages

Description
Starting with basic principles, this reference and handbook discusses examples of the most advanced models of bacterial infection with regard to their value as paradigms to understand the molecular cross-talks between microbes and their host and tissue targets. It adopts a very forward-looking, advanced approach, placing special emphasis on the main global challenges facing scientists today, such as pathogenicity vs. commensalisms, infections in immunocompromised hosts and species specificity issues.
About the Author
Professor Sansonetti received his M.D. in 1979 from the University of Paris. From 1979 to 1981, he conducted research in the Department of Enteric Infections at the Walter Reed Army Institute of Research in the United States. He is a Chevalier de la Legion d'Honneur and received the Prix d'Excellence Jacques Monod en Biologie Moleculaire, the Prix AGIR du Conseil Pasteur-Weitzmann, the Grand Prix de l'Academie de Medecine, the Prix Louis Jeantet de Medecine, and the Robert Koch Prize and Medal. He is a member of the French Academy of Science and a corresponding member of the French Academy of Medicine. In 2007, he was elected to the American Academy of Arts and Sciences. He is currently professor at the Institute Pasteur and head of the Unite de Pathogenie Microbienne Moleculaire at the Pasteur Institute of Paris.