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Protein Oxidation and Aging

ISBN: 978-1-118-49301-4

November 2012

516 pages

Description
As the lifespan of humans increases, research into aging and its related pathological conditions is gaining momentum. This book is the first to explain protein oxidation and the aging process, focusing on the connection between protein disturbances and the oxidative stress that cells continually undergo. Coverage includes major and novel techniques that can be used to analyze protein oxidation, how protein oxidation products can be biomarkers of aging, and the very broad involvement of protein oxidation in such diseases as Alzheimer's, Parkinson's, cardiovascular disease, diabetes, and cancer.
About the Author

TILMAN GRUNE, MD, is Full Professor and Director of the Institute of Nutrition at Friedrich Schiller University Jena. His research examines the biological phenomenon of oxidative stress. In particular, his research group has been investigating the oxidative stress response of cells and organisms and the protective influence of antioxidants.

BETUL CATALGOL, MD, is Assistant Professor in the Faculty of Medicine and the Department of Biochemistry at Marmara University. She is coauthor of Proteasome and Neurodegenerative Diseases, Proteasome and Cancer, and Protein Carbonyl Measurement by Enzyme-Linked Immunosorbent Assay.

TOBIAS JUNG, PhD, is a Research Assistant at Friedrich Schiller University Jena. He is coauthor of Structure of the Proteasome.